Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447092 | 0.93 | MAPT (0.59) | MAPTALDH1A1HTTFAAHACHE | |
| SCHEMBL564270 | 0.93 | MAPT (0.59) | MAPTALDH1A1HTTFAAHACHE | |
| SCHEMBL650225 | 0.87 | POLB (0.47) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL27167067 | 0.82 | POLB (0.57) | MAPTMEN1KMT2ARAB9ACTSV | |
| SCHEMBL29751809 | 0.80 | POLB (0.48) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL1583614 | 0.80 | POLB (0.48) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2305236 | 0.79 | NPC1 (0.68) | ALDH1A1HTTMEN1KMT2ARAB9A | |
| SCHEMBL30015078 | 0.79 | NPC1 (0.68) | ALDH1A1HTTMEN1KMT2ARAB9A | |
| SCHEMBL30008070 | 0.79 | POLB (0.56) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL3994909 | 0.79 | POLB (0.56) | MAPTALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126613-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-03-01 | — | — | CN | disclosed |