SCHEMBL2305236

SCHEMBL2305236

O=[N+]([O-])c1ccccc1OCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 3/20 0.68
▸ RAB9A P51151 3/20 0.68
▸ RECQL P46063 1/20 0.68
▸ POLB P06746 3/20 0.61
▸ TDP1 Q9NUW8 2/20 0.61
▸ SENP8 Q96LD8 1/20 0.61
▸ SENP7 Q9BQF6 1/20 0.61
▸ SENP6 Q9GZR1 1/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.61
▸ KDM4E B2RXH2 2/20 0.60
▸ HTR1A P08908 1/20 0.59
▸ ADRA1D P25100 1/20 0.59
▸ ADRA1A P35348 1/20 0.59
▸ ADRA1B P35368 1/20 0.59
▸ ALDH1A1 P00352 5/20 0.58
▸ KMT2A Q03164 4/20 0.58
▸ MEN1 O00255 3/20 0.58
▸ KCNH2 Q12809 1/20 0.56
▸ SGMS2 Q8NHU3 1/20 0.55
▸ HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30015078 1.00 NPC1 (0.68) NPC1RAB9ARECQLPOLBTDP1
SCHEMBL13230076 0.94 NPC1 (0.75) NPC1RAB9ARECQLPOLBTDP1
SCHEMBL30069258 0.88 NPC1 (0.62) NPC1RAB9ARECQLPOLBTDP1
SCHEMBL27457885 0.87 NPC1 (0.60) NPC1RAB9ARECQLPOLBTDP1
SCHEMBL14988733 0.87 RAB9A (0.60) NPC1RAB9ARECQLPOLBTDP1
SCHEMBL18429648 0.87 NPC1 (0.60) NPC1RAB9ARECQLPOLBTDP1
SCHEMBL11121016 0.87 NPC1 (0.60) NPC1RAB9ARECQLPOLBTDP1
SCHEMBL9528862 0.87 HTR1A (0.54) NPC1RAB9ARECQLPOLBTDP1
SCHEMBL31434580 0.87 RAB9A (0.60) NPC1RAB9ARECQLPOLBTDP1
SCHEMBL27388637 0.86 HTR1A (0.55) NPC1RAB9ARECQLPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2349442-B1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE UNIV TENNESSEE RES FOUND (US) 2023-07-26 — — EP claimed
US-11686722-B2 Compositions and methods to detect molecules in a sample INFUSENSE CORP. (US) 2023-06-27 — — US claimed
EP-3629928-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE The University of Tennessee Research Foundation (US) 2020-04-08 — — EP claimed
US-20190331656-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE INFUSENSE CORP. 2019-10-31 — — US claimed
EP-3555609-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE Infusense Corp. (US) 2019-10-23 — — EP claimed
CN-109721586-A A kind of 5- benzyl -3- pyridyl group -1H-1,2,4- triazole class compounds and its preparation method and application 中国医科大学 2019-05-07 — — CN claimed
WO-2018222820-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-12-06 — — WO claimed
US-20180271413-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE UNITED STATES GOVERNMENT 2018-09-27 — — US claimed
WO-2018112458-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE INFUSENSE CORP. (US) 2018-06-21 — — WO claimed
US-9983162-B2 Method and device for detection of bioavailable drug concentration THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-05-29 — — US claimed
US-20170370880-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE UNITED STATES GOVERNMENT 2017-12-28 — — US claimed
US-20150119848-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY 2015-04-30 — — US claimed
EP-2856133-A1 IMPROVED METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION The University of Tennessee Research Foundation (US) 2015-04-08 — — EP claimed
WO-2013180814-A1 IMPROVED METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-12-05 — — WO claimed
US-20120116195-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2012-05-10 — — US claimed
EP-2349442-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE University of Tennessee Research Foundation (US) 2011-08-03 — — EP claimed
US-20100121210-A1 METHOD AND DEVICE FOR DETECTION OFANALYTE IN VAPOR OR GASEOUS SAMPLE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) 2010-05-13 — — US claimed
WO-2010045458-A1 METHOD AND DEVICE FOR DETECTION OF ANALYTE IN VAPOR OR GASEOUS SAMPLE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) 2010-04-22 — — WO claimed
WO-2010045465-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2010-04-22 — — WO claimed
EP-2349442-B1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE UNIV TENNESSEE RES FOUND (US) 2023-07-26 — — EP disclosed
US-11686722-B2 Compositions and methods to detect molecules in a sample INFUSENSE CORP. (US) 2023-06-27 — — US disclosed
US-11375929-B2 Method and device for detection of bioavailable drug concentration in a fluid sample THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2022-07-05 — — US disclosed
CN-108430994-B Compounds, compositions and methods for modulating CFTR 蛋白质平衡治疗股份有限公司 2022-04-12 — — CN disclosed
EP-3629928-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE The University of Tennessee Research Foundation (US) 2020-04-08 — — EP disclosed
US-20190331656-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE INFUSENSE CORP. 2019-10-31 — — US disclosed
EP-3555609-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE Infusense Corp. (US) 2019-10-23 — — EP disclosed
WO-2018222820-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-12-06 — — WO disclosed
US-20180271413-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE UNITED STATES GOVERNMENT 2018-09-27 — — US disclosed
WO-2018112458-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE INFUSENSE CORP. (US) 2018-06-21 — — WO disclosed
US-9983162-B2 Method and device for detection of bioavailable drug concentration THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-05-29 — — US disclosed
US-20170370880-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE UNITED STATES GOVERNMENT 2017-12-28 — — US disclosed
US-9700246-B2 Method and device for detection of bioavailable drug concentration in a fluid sample THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2017-07-11 — — US disclosed
CN-104661762-B Pattern forming method, electronic wiring board, optical element, and pattern forming apparatus 富士胶片株式会社 2016-11-09 — — CN disclosed
CN-104661762-A Pattern forming method, electronic wiring board, optical element, and pattern forming apparatus FUJIFILM CORP 2015-05-27 — — CN disclosed
US-20150119848-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY 2015-04-30 — — US disclosed
EP-2856133-A1 IMPROVED METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION The University of Tennessee Research Foundation (US) 2015-04-08 — — EP disclosed
CN-102887880-B Dibenzofuran derivatives, and preparation method and application thereof SOUTHEAST UNIVERSITY (CN) 2014-10-29 — — CN disclosed
WO-2013180814-A1 IMPROVED METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-12-05 — — WO disclosed
EP-2123627-B1 PROCESS FOR PRODUCING AROMATIC AMINE HAVING ARALKYLOXY OR HETEROARALKYLOXY GROUP UBE INDUSTRIES (JP) 2013-11-20 — — EP disclosed
CN-102887880-A Dibenzofuran derivatives, and preparation method and application thereof UNIV SOUTHEAST 2013-01-23 — — CN disclosed
CN-102736437-A Pattern formation apparatus and pattern formation method FUJIFILM CORP 2012-10-17 — — CN disclosed
US-20120116195-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2012-05-10 — — US disclosed
EP-2349442-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE University of Tennessee Research Foundation (US) 2011-08-03 — — EP disclosed
US-20100121210-A1 METHOD AND DEVICE FOR DETECTION OFANALYTE IN VAPOR OR GASEOUS SAMPLE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) 2010-05-13 — — US disclosed
WO-2010045458-A1 METHOD AND DEVICE FOR DETECTION OF ANALYTE IN VAPOR OR GASEOUS SAMPLE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) 2010-04-22 — — WO disclosed
WO-2010045465-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2010-04-22 — — WO disclosed
US-7655657-B2 Fused bicycloheterocycle substituted quinuclidine derivatives ABBOTT LABORATORIES (US) 2010-02-02 — — US disclosed
EP-2123627-A1 PROCESS FOR PRODUCING AROMATIC AMINE HAVING ARALKYLOXY OR HETEROARALKYLOXY GROUP Ube Industries, Ltd. (JP) 2009-11-25 — — EP disclosed
US-20080064703-A1 Fused bicycloheterocycle substituted quinuclidine derivatives ABBVIE INC. 2008-03-13 — — US disclosed
US-7262318-B2 Substituted heteroaryl- and phenylsulfamoyl compounds PFIZER, INC. (US) 2007-08-28 — — US disclosed
EP-1147093-B1 SUBSTITUTED BICYCLIC DERIVATIVES USEFUL AS ANTICANCER AGENTS PFIZER PROD INC (US) 2007-04-11 — — EP disclosed
US-20070060588-A1 Fused bicycloheterocycle substituted quinuclidine derivatives ABBOTT LABORATORIES 2007-03-15 — — US disclosed
US-20070054909-A1 VLA-4 inhibitor compounds DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 — — US disclosed
US-7179819-B2 VLA-4 inhibitor compounds DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-02-20 — — US disclosed
EP-1206288-B1 TARGETED FIBERLESS RADIATIVE EFFECTORS UNIV MICHIGAN (US) 2007-01-10 — — EP disclosed
EP-1725524-A1 SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS Pfizer Products Incorporated (US) 2006-11-29 — — EP disclosed
US-20060258723-A1 Substituted Heteroaryl- and Phenylsulfamoyl Compounds PFIZER INC 2006-11-16 — — US disclosed
EP-0983288-B1 SYNTHESIS OF OLIGONUCLEOTIDES QUIATECH AB (SE) 2006-07-12 — — EP disclosed
US-20050228015-A1 Substituted heteroaryl- and phenylsulfamoyl compounds PFIZER INC 2005-10-13 — — US disclosed
WO-2005092845-A1 SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS PFIZER PRODUCTS INC. (US) 2005-10-06 — — WO disclosed
US-6933390-B2 Process for the arylation of aza-heterocycles with activated aromatics in presence of caesium carbonate WARNER-LAMBERT COMPANY (US) 2005-08-23 — — US disclosed
US-6867201-B2 Heteroaromatic bicyclic derivatives useful as anticancer agents PFIZER INC (US) 2005-03-15 — — US disclosed
EP-1189612-A4 VLA-4 INHIBITOR COMPOUNDS DAIICHI SEIYAKU CO (JP) 2005-02-16 — — EP disclosed
US-20040249185-A1 Process for the arylation of aza-heterocycles with activated aromatics in presence of caesium carbonate BARTH HUBERT (DE) 2004-12-09 — — US disclosed
US-20040229858-A1 VLA-4 inhibitor compounds DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-11-18 — — US disclosed
US-6790946-B2 GENERATING IMMBOLIZED NUCLEOTIDE SEQUENCES; OBTAIN NUCLEOTIDE SEQUENCES, ATTACH TO SOLID SUPPORT, RELEASE TERMINAL OF OLIGONUCLEOTIDE QUIATECH AB (SE) 2004-09-14 — — US disclosed
US-6774242-B1 REACTING WITH INDOLE IN APROTIC SOLVENT GOEDECKE GMBH (DE) 2004-08-10 — — US disclosed
US-6756378-B2 BENZYL -UREA, -THIOUREA, OR -GUANIDINE DERIVATIVES THAT INHIBIT THE BINDING OF LIGANDS TO ALPHA 4 BETA 1 INTEGRIN (VLA-4) PHARMACOPEIA DRUG DISCOVERY, INC. 2004-06-29 — — US disclosed
EP-1396489-A1 Heteroaromatic bicyclic derivatives useful as anticancer agents Pfizer Products Inc. (US) 2004-03-10 — — EP disclosed
EP-1029853-B1 Heteroaromatic bicyclic derivatives useful as anticancer agents PFIZER PROD INC (US) 2004-02-25 — — EP disclosed
EP-1360007-A1 METHOD FOR THE PREPARATION OF OPTICAL (BIO)CHEMICAL SENSOR DEVICES Vir A/S (DK) 2003-11-12 — — EP disclosed
US-20030186995-A1 Substituted bicyclic derivatives useful as anticancer agents PFIZER INC. 2003-10-02 — — US disclosed
US-20030078249-A1 VLA-4 inhibitor compounds DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-04-24 — — US disclosed
US-6541481-B2 A quinazoline compound PFIZER INC 2003-04-01 — — US disclosed
US-20030055049-A1 Heteroaromatic bicyclic derivatives useful as anticancer agents PFIZER INC. 2003-03-20 — — US disclosed
WO-2003012500-A1 MATERIALS FOR POLYMER OPTICAL FIBERS RPO PTY LIMITED (AU) 2003-02-13 — — WO disclosed
CN-1391473-A VLA-4 inhibitor compounds DAIICHI SEIYAKU CO (JP) 2003-01-15 — — CN disclosed
US-6465449-B1 SUCH AS (6-(4-(6-AMINO-3-AZA-BICYCLO(3.1.0)HEX-3-YLMETHYL)-PHENYL)-QUINAZOLIN-4-YL) -(4-PHENOXY-PHENYL)-AMINE PFIZER INC. 2002-10-15 — — US disclosed
WO-2002066162-A1 METHOD FOR THE PREPARATION OF OPTICAL (BIO)CHEMICAL SENSOR DEVICES VIR A/S (DK) 2002-08-29 — — WO disclosed
US-20020115224-A1 Method for the preparation of optical (bio)chemical sensor devices VIR A/S (DK) 2002-08-22 — — US disclosed
EP-1206288-A2 TARGETED FIBERLESS RADIATIVE EFFECTORS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2002-05-22 — — EP disclosed
US-20020051994-A1 Synthesis of oligonucleotides KWIATKOWSKI MAREK (SE) 2002-05-02 — — US disclosed
US-6379955-B1 Optical fiberless sensors REGENTS OF THE UNIVERSITY OF MICHIGAN 2002-04-30 — — US disclosed
EP-1189612-A1 VLA-4 INHIBITOR COMPOUNDS Daiichi Pharmaceutical Co., Ltd. (JP) 2002-03-27 — — EP disclosed
EP-1165512-A2 METHOD FOR ARYLATING AZA-HETEROCYCLES WITH ACTIVATED AROMATIC COMPOUNDS IN THE PRESENCE OF CESIUM CARBONATE GÖDECKE GMBH (DE) 2002-01-02 — — EP disclosed
US-6313284-B1 Solid phase synthesis MAREK KWIATKOWSKI (SE) 2001-11-06 — — US disclosed
US-20010034351-A1 Substituted bicyclic derivatives useful as anticancer agents KATH JOHN CHARLES (US) 2001-10-25 — — US disclosed
EP-1147093-A1 SUBSTITUTED BICYCLIC DERIVATIVES USEFUL AS ANTICANCER AGENTS Pfizer Products Inc. (US) 2001-10-24 — — EP disclosed
US-6284764-B1 ANTIPROLIFERATIVE AGENT PFIZER INC. 2001-09-04 — — US disclosed
WO-2001008660-A2 TARGETED FIBERLESS RADIATIVE EFFECTORS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2001-02-08 — — WO disclosed
WO-2001000206-A1 VLA-4 INHIBITOR COMPOUNDS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-01-04 — — WO disclosed
WO-2000059883-A2 METHOD FOR PRODUCING N-ARYL-AZA-HETEROCYCLES IN THE PRESENCE OF CESIUM CARBONATE Gödecke GmbH (DE) 2000-10-12 — — WO disclosed
EP-1029853-A1 Heteroaromatic bicyclic derivatives useful as anticancer agents Pfizer Products Inc. (US) 2000-08-23 — — EP disclosed
WO-2000044728-A1 SUBSTITUTED BICYCLIC DERIVATIVES USEFUL AS ANTICANCER AGENTS PFIZER PRODUCTS INC. (US) 2000-08-03 — — WO disclosed
US-6046183-A SYNERGISTIC MIXTURE OF FINASTERIDE AND DOXAZOSIN MERCK & CO., INC. (US) 2000-04-04 — — US disclosed
EP-0983288-A1 SYNTHESIS OF OLIGONUCLEOTIDES Kwiatkowski, Marek (SE) 2000-03-08 — — EP disclosed
US-5994362-A ADMINISTERING FINASTERIDE AND CASODEX MERCK & CO., INC. (US) 1999-11-30 — — US disclosed
EP-0469833-B1 N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them LILLY CO ELI (GB) 1999-09-08 — — EP disclosed
WO-1998051698-A1 SYNTHESIS OF OLIGONUCLEOTIDES KWIATKOWSKI MAREK (SE) 1998-11-19 — — WO disclosed
US-5753641-A SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS MERCK & CO., INC. (US) 1998-05-19 — — US disclosed
US-5622969-A ADMINISTERING TO HUMAN OR ANIMAL SUFFERING FROM ALLERGIC REACTION OF PULMONARY SYSTEM AND OTHER INFLAMMATORY DISORDERS ELI LILLY AND COMPANY (US) 1997-04-22 — — US disclosed
US-5569764-A USEFUL FOR TREATING ALLERGIC REACTIONS OF PULMONARY SYSTEM, ALLERGIC SKIN DISEASES, RHEUMATIC FEVER, CYSTIC FIBROSIS, AND VASCULAR DISEASES ELI LILLY AND COMPANY (US) 1996-10-29 — — US disclosed
EP-0335274-B1 Formation of nitrophenyl ethers from polyols and nitroanisoles DOW CHEMICAL CO (US) 1996-03-13 — — EP disclosed
US-5486612-A FOR TREATING DISEASES WHICH LEUKOTRIENES MEDIATE ELI LILLY AND COMPANY (US) 1996-01-23 — — US disclosed
EP-0658554-A1 N-benzyl dihydroindole LTD4 antagonists ELI LILLY AND COMPANY (US) 1995-06-21 — — EP disclosed
US-5281593-A Pharmaceuticals LILLY INDUSTRIES LIMITED (GB) 1994-01-25 — — US disclosed
EP-0576603-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO. INC. (US) 1994-01-05 — — EP disclosed
EP-0526093-A1 New non-steroidal agents as 5-alpha reductase inhibitors MERCK & CO. INC. (US) 1993-02-03 — — EP disclosed
WO-1992018132-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA COMTAINING A 5 ALPHA-REDUCTASE INHIBITOR MERCK & CO., INC. (US) 1992-10-29 — — WO disclosed
WO-1992016213-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO., INC. (US) 1992-10-01 — — WO disclosed
WO-1992016233-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC CANCER CONTAINING A 5 ALPHA REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO., INC. (US) 1992-10-01 — — WO disclosed
US-5116851-A Administering antiischemic and antiarrhythmia agents E. R. SQUIBB & SONS, INC. (US) 1992-05-26 — — US disclosed
EP-0469833-A1 N-Benzyl-Indoles, processes for their preparation and pharmaceutical compositions containing them LILLY INDUSTRIES LIMITED (GB) 1992-02-05 — — EP disclosed
EP-0453658-A2 Use of substituted anilides and sulfonamides in the treatment of cardiovascular diseases E.R. SQUIBB & SONS, INC. (US) 1991-10-30 — — EP disclosed
US-4960950-A Formation of nitrophenyl ethers from polyols and nitroanisoles THE DOW CHEMICAL COMPANY (US) 1990-10-02 — — US disclosed
EP-0360566-A2 Lipoxygenase/cyclooxygenase inhibiting benzoxazolones PFIZER INC. (US) 1990-03-28 — — EP disclosed
EP-0335274-A2 Formation of nitrophenyl ethers from polyols and nitroanisoles THE DOW CHEMICAL COMPANY (US) 1989-10-04 — — EP disclosed
EP-0335274-A2 Formation of nitrophenyl ethers from polyols and nitroanisoles THE DOW CHEMICAL COMPANY (US) 1989-10-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078249-A1 VLA-4 inhibitor compounds VCAM1, ICAM1, ITGA4 NPC1 2939/4885RAB9A 2282/4885RECQL 4883/4885
US-20050228015-A1 Substituted heteroaryl- and phenylsulfamoyl compounds PPARA, PPARG, PPARD NPC1 59/4885RAB9A 2271/4885RECQL 4170/4885
US-20070054909-A1 VLA-4 inhibitor compounds VCAM1, ITGB4, ICAM1 NPC1 3300/4885RAB9A 1984/4885RECQL 4883/4885
US-20070060588-A1 Fused bicycloheterocycle substituted quinuclidine derivatives CHRNA1, CHRNA7, CHRNA2 NPC1 757/4885RAB9A 807/4885RECQL 1177/4885
US-20030186995-A1 Substituted bicyclic derivatives useful as anticancer agents CCNA1, MCL1, RCC1 NPC1 284/4885RAB9A 1540/4885RECQL 299/4885
US-20040249185-A1 Process for the arylation of aza-heterocycles with activated aromatics in presence of caesium carbonate AZI2, KCNH1, CA7 NPC1 3071/4885RAB9A 1479/4885RECQL 3995/4885
US-20060258723-A1 Substituted Heteroaryl- and Phenylsulfamoyl Compounds PPARG, PPARA, PPARD NPC1 74/4885RAB9A 2063/4885RECQL 4086/4885
US-20020051994-A1 Synthesis of oligonucleotides RNGTT, POLR2H, POLR2E NPC1 4490/4885RAB9A 4781/4885RECQL 1462/4885
US-20080064703-A1 Fused bicycloheterocycle substituted quinuclidine derivatives IDO1, IDO2, HTR3C NPC1 2803/4885RAB9A 847/4885RECQL 2848/4885
US-20040229858-A1 VLA-4 inhibitor compounds VCAM1, ICAM1, ITGB4 NPC1 2981/4885RAB9A 2225/4885RECQL 4883/4885
US-20030055049-A1 Heteroaromatic bicyclic derivatives useful as anticancer agents RCC1, CCNA1, MCL1 NPC1 390/4885RAB9A 2403/4885RECQL 321/4885
US-20010034351-A1 Substituted bicyclic derivatives useful as anticancer agents CCNA1, MCL1, RCC1 NPC1 284/4885RAB9A 1540/4885RECQL 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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