SCHEMBL28700283

SCHEMBL28700283

CCCCC(NC)C(=O)NCCc1ccc(-c2ccc(Cl)cc2)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.47
METAP2 P50579 7/20 0.46
METAP1 P53582 4/20 0.46
CNR1 P21554 1/20 0.44
KMT2A Q03164 1/20 0.41
MMP2 P08253 3/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
HPGD P15428 1/20 0.40
PLAAT3 P53816 1/20 0.39
PLAAT5 Q96KN8 1/20 0.39
PLAAT2 Q9NWW9 1/20 0.39
PLAAT4 Q9UL19 1/20 0.39
MMP3 P08254 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28706787 0.89 CNR1 (0.47) KCNH2METAP2METAP1CNR1KMT2A
SCHEMBL28684177 0.85 KCNH2 (0.62) KCNH2METAP2METAP1CNR1PLAAT3
SCHEMBL27212684 0.84 KCNH2 (0.67) KCNH2MMP2CA1CA2HPGD
Hydrochloric Acid SCHEMBL29386316 0.83 KCNH2 (0.68) KCNH2MMP2CA1CA2HPGD
SCHEMBL28690363 0.78 KCNH2 (0.58) KCNH2METAP2METAP1CNR1KMT2A
SCHEMBL28706018 0.77 KCNH2 (0.52) KCNH2METAP2METAP1
SCHEMBL27212686 0.77 KCNH2 (0.73) KCNH2CNR1KMT2AMMP2CA1
Hydrochloric Acid SCHEMBL29386314 0.76 KCNH2 (0.74) KCNH2CNR1KMT2AMMP2CA1
SCHEMBL30558889 0.74 SPHK1 (0.47) KCNH2CNR1KMT2AMMP2CA1
SCHEMBL27212672 0.74 SPHK1 (0.47) KCNH2CNR1KMT2AMMP2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114051496-A Derivative compound for introducing biphenyl group into novel amino alkanoic acid and antifungal pharmaceutical composition comprising same 阿米蒂比奥有限公司 2022-02-15 CN claimed
CN-114051496-A Derivative compound for introducing biphenyl group into novel amino alkanoic acid and antifungal pharmaceutical composition comprising same 阿米蒂比奥有限公司 2022-02-15 CN disclosed