Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28684177 | 0.90 | KCNH2 (0.62) | KCNH2DPP7HDAC8METAP2METAP1 | |
| SCHEMBL27212676 | 0.82 | KCNH2 (0.68) | KCNH2DPP7SPHK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29385897 | 0.81 | KCNH2 (0.69) | KCNH2DPP7SPHK1ALDH1A1 | |
| SCHEMBL28693951 | 0.81 | ERAP2 (0.52) | KCNH2SPHK1CHEK1 | |
| SCHEMBL28700283 | 0.77 | KCNH2 (0.47) | KCNH2METAP2METAP1 | |
| SCHEMBL28690363 | 0.77 | KCNH2 (0.58) | KCNH2HDAC8METAP2METAP1HTT | |
| SCHEMBL29696192 | 0.76 | KCNH2 (0.87) | KCNH2DPP7HDAC8SPHK1 | |
| SCHEMBL27212681 | 0.76 | KCNH2 (0.87) | KCNH2DPP7HDAC8SPHK1 | |
| SCHEMBL14920505 | 0.76 | TSHR (0.56) | LMNAMAPK1NLRP1ALDH1A1P2RX7 | |
| Hydrochloric Acid SCHEMBL29385528 | 0.75 | KCNH2 (0.87) | KCNH2DPP7HDAC8SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114051496-B | Derivative compounds for introducing biphenyl into novel amino alkanoic acids and antifungal pharmaceutical compositions containing the same | 阿米蒂比奥有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-114051496-A | Derivative compound for introducing biphenyl group into novel amino alkanoic acid and antifungal pharmaceutical composition comprising same | 阿米蒂比奥有限公司 | 2022-02-15 | — | — | CN | claimed |
| CN-116887821-A | Derivative compound for introducing biphenyl into novel amino alkanoic acid and anti-inflammatory composition containing the same | 阿米蒂比奥有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-114051496-B | Derivative compounds for introducing biphenyl into novel amino alkanoic acids and antifungal pharmaceutical compositions containing the same | 阿米蒂比奥有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-114051496-A | Derivative compound for introducing biphenyl group into novel amino alkanoic acid and antifungal pharmaceutical composition comprising same | 阿米蒂比奥有限公司 | 2022-02-15 | — | — | CN | disclosed |