Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.53 |
| ▸ | MAOA | P21397 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346860 | 0.76 | SLC6A4 (0.56) | SLC6A4MAOAMAOB | |
| SCHEMBL17688579 | 0.76 | SLC6A4 (0.50) | SLC6A4MAOAMAOBHTR2AHTR2C | |
| SCHEMBL17688578 | 0.76 | SLC6A4 (0.50) | SLC6A4MAOAMAOBHTR2AHTR2C | |
| SCHEMBL13175896 | 0.76 | SLC6A4 (0.53) | SLC6A4MAOAMAOBPTGS2 | |
| SCHEMBL11076527 | 0.75 | SLC6A4 (0.48) | SLC6A4MAOA | |
| SCHEMBL835786 | 0.75 | SLC6A4 (0.53) | SLC6A4MAOAHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL17710304 | 0.75 | SLC6A4 (0.49) | SLC6A4MAOAMAOBHTR2AHTR2C | |
| SCHEMBL20468698 | 0.75 | SLC6A4 (0.53) | SLC6A4MAOAMAOBHTR2AHTR2C | |
| SCHEMBL20468699 | 0.75 | SLC6A4 (0.53) | SLC6A4MAOAMAOBHTR2AHTR2C | |
| SCHEMBL17710314 | 0.73 | SLC6A4 (0.47) | SLC6A4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463458-B | Modulators of ROR-gamma | 生命医药有限责任公司 | 2022-02-01 | — | — | CN | disclosed |