SCHEMBL346860

SCHEMBL346860

CCSc1ccc(SCC)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 9/20 0.56
MAOA P21397 3/20 0.56
GSK3B P49841 1/20 0.44
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
SLC2A1 P11166 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA13 Q8N1Q1 1/20 0.38
GAA P10253 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
GRK6 P43250 1/20 0.37
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8591154 0.91 SLC6A4 (0.50) SLC6A4MAOAGSK3BRAB9ANPC1
SCHEMBL10316183 0.91 SLC6A4 (0.50) SLC6A4MAOAGSK3BRAB9ANPC1
SCHEMBL9793575 0.91 SLC6A4 (0.50) SLC6A4MAOAGSK3BRAB9ANPC1
SCHEMBL169195 0.88 SLC6A4 (0.48) SLC6A4MAOARAB9ANPC1ALDH1A1
SCHEMBL13940796 0.88 SLC6A4 (0.48) SLC6A4MAOAALDH1A1
SCHEMBL3371540 0.86 NR1H2 (0.50) SLC6A4MAOARAB9ANPC1ALDH1A1
SCHEMBL19454683 0.86 SLC6A4 (0.52) SLC6A4MAOAGSK3BRAB9ANPC1
SCHEMBL5609805 0.86 SLC6A4 (0.47) SLC6A4MAOAGSK3BRAB9ANPC1
SCHEMBL96478 0.86 SLC6A4 (0.47) SLC6A4MAOAGSK3BRAB9ANPC1
SCHEMBL4523181 0.86 SLC6A4 (0.52) SLC6A4MAOARAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
US-7306898-B2 Planographic printing method and planographic printing plate precursor used therein FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-7306898-B2 Planographic printing method and planographic printing plate precursor used therein FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
EP-1767560-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER Sumitomo Chemical Company, Limited (JP) 2007-03-28 EP disclosed
US-5032489-A Optically functional element Kobayashi, Eiichi (JP) 1991-07-16 US disclosed
EP-0194798-B1 OPTICALLY FUNCTIONAL ELEMENTS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-06-21 EP disclosed
EP-0194798-A1 Optically functional elements MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-09-17 EP disclosed
US-4188274-A DECARBOXYLATION STANDARD OIL COMPANY (INDIANA) (US) 1980-02-12 US disclosed
US-4174447-A SILVER SALTS OF CARBOXY ACIDS STANDARD OIL COMPANY (INDIANA) (US) 1979-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR SLC6A4 4625/4885MAOA 2/4885GSK3B 1721/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR SLC6A4 4606/4885MAOA 2/4885GSK3B 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.