Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.72 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL21067307 | 1.00 | DNM1 (0.72) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Dodecylamine SCHEMBL27696549 | 1.00 | DNM1 (0.72) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Octadecylamine SCHEMBL28250639 | 1.00 | DNM1 (0.72) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Butylamine SCHEMBL27571619 | 0.88 | — | — | |
| Guanidine SCHEMBL27317151 | 0.88 | SPHK2 (0.68) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Dodecylamine SCHEMBL25308253 | 0.85 | DNM1 (0.87) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Methyl Alcohol SCHEMBL28365635 | 0.85 | — | — | |
| Dodecylamine SCHEMBL30648425 | 0.85 | DNM1 (0.87) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Methyl Alcohol SCHEMBL3390948 | 0.85 | DNM1 (0.87) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| Tetradecylamine SCHEMBL17238770 | 0.85 | DNM1 (0.87) | DNM1TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114158553-B | Novel pesticide preparation and preparation method thereof | 南开沧州渤海新区绿色化工研究有限公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-114158553-A | Novel pesticide preparation and preparation method thereof | 南开沧州渤海新区绿色化工研究有限公司 | 2022-03-11 | — | — | CN | disclosed |