Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063695 | 0.96 | GAA (0.46) | GAACA9CA12CA1CA2 | |
| SCHEMBL28418447 | 0.96 | GAA (0.46) | GAACA9CA12CA1CA2 | |
| Lithium Ion SCHEMBL16267471 | 0.82 | GAA (0.62) | GAACA9CA12CA1CA2 | |
| SCHEMBL1660714 | 0.79 | GAA (0.65) | GAACA9CA12CA1CA2 | |
| SCHEMBL30272576 | 0.79 | GAA (0.65) | GAACA9CA12CA1CA2 | |
| Lithium Ion SCHEMBL20420825 | 0.79 | TTR (0.63) | GAATTRNR4A1NSD2 | |
| SCHEMBL7761041 | 0.77 | CA2 (0.67) | GAACA9CA12CA1CA2 | |
| SCHEMBL2287880 | 0.77 | GAA (0.62) | GAACA9CA12CA1CA2 | |
| SCHEMBL6392445 | 0.77 | GAA (0.62) | GAACA9CA12CA1CA2 | |
| Potassium Ion SCHEMBL15194289 | 0.77 | GAA (0.62) | GAACA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110350164-B | Multiphase composite high-nickel ternary positive electrode material and preparation method thereof | 湖南省正源储能材料与器件研究所 | 2023-06-06 | — | — | CN | claimed |
| CN-114188515-A | Polymer-coated high-nickel ternary cathode material and preparation method and application thereof | 厦门大学 | 2022-03-15 | — | — | CN | claimed |
| CN-110350164-B | Multiphase composite high-nickel ternary positive electrode material and preparation method thereof | 湖南省正源储能材料与器件研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-110350164-B | Multiphase composite high-nickel ternary positive electrode material and preparation method thereof | 湖南省正源储能材料与器件研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-114188515-A | Polymer-coated high-nickel ternary cathode material and preparation method and application thereof | 厦门大学 | 2022-03-15 | — | — | CN | disclosed |