SCHEMBL28700892

SCHEMBL28700892

O=[N+]([O-])c1ccc(SS(=O)(=O)c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.57
CA2 P00918 8/20 0.53
CA1 P00915 7/20 0.53
CA9 Q16790 6/20 0.53
CA12 O43570 5/20 0.53
CA14 Q9ULX7 4/20 0.53
CA3 P07451 3/20 0.53
CA4 P22748 3/20 0.53
CA6 P23280 3/20 0.53
CA5A P35218 3/20 0.53
CA7 P43166 3/20 0.53
CA13 Q8N1Q1 3/20 0.53
CA5B Q9Y2D0 3/20 0.53
ACHE P22303 2/20 0.49
BCHE P06276 1/20 0.49
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7115923 0.91 DNMT1 (0.73) DNMT1CA2CA1CA9CA12
SCHEMBL29400498 0.81 CA2 (0.59) CA2CA1CA9CA12CA14
SCHEMBL29446569 0.80 CA1 (0.48) CA2CA1CA9CA12CA14
SCHEMBL7113458 0.80 CA1 (0.48) CA2CA1CA9CA12CA14
SCHEMBL29420428 0.79 CA2 (0.57) CA2CA1CA9CA12CA14
SCHEMBL11343833 0.78 CA1 (0.47) CA2CA1CA9CA12CA14
SCHEMBL15434708 0.78 CA2 (0.55) CA2CA1CA9CA12CA14
SCHEMBL29376053 0.78 CA2 (0.55) CA2CA1CA9CA12CA14
SCHEMBL30195022 0.78 CA2 (0.55) CA2CA1CA9CA12CA14
SCHEMBL8934655 0.76 MAPT (0.76) CA2CA1CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213298-B Method for preparing thiosulfonate compound by directly oxidizing thiophenol 南昌大学 2022-12-06 CN disclosed
CN-114213298-A Method for preparing thiosulfonate compound by directly oxidizing thiophenol 南昌大学 2022-03-22 CN disclosed