Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.59 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 8/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208051 | 0.78 | CAPN1 (0.59) | CAPN1CAPN2TSHRKDM4EMEN1 | |
| SCHEMBL3741787 | 0.78 | KMT2A (0.56) | CAPN1CAPN2MEN1NPC1USP2 | |
| SCHEMBL29935857 | 0.78 | CAPN1 (0.59) | CAPN1CAPN2TSHRKDM4EMEN1 | |
| SCHEMBL19178972 | 0.78 | TDO2 (0.78) | CAPN1CAPN2TSHRKDM4EMEN1 | |
| SCHEMBL21665304 | 0.78 | CAPN1 (0.59) | CAPN1CAPN2NOTUMTSHRKDM4E | |
| SCHEMBL31448093 | 0.78 | TDO2 (0.78) | CAPN1CAPN2TSHRKDM4EMEN1 | |
| SCHEMBL5912516 | 0.77 | KDM4E (0.64) | CAPN1CAPN2NOTUMTSHRKDM4E | |
| SCHEMBL787960 | 0.77 | CYP2A6 (0.59) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13957453 | 0.76 | CAPN1 (0.56) | CAPN1CAPN2TSHRKDM4EMEN1 | |
| SCHEMBL352269 | 0.76 | TDO2 (0.57) | CAPN1CAPN2NOTUMTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108329311-B | Tricyclic compound as selective estrogen receptor down-regulator and application thereof | 南京圣和药业股份有限公司 | 2022-02-22 | — | — | CN | disclosed |