Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.64 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699763 | 0.92 | PTGER4 (0.73) | PTGER4PTGER2POLBKCNQ3KCNQ2 | |
| SCHEMBL24861822 | 0.90 | PTGER4 (0.76) | PTGER4PTGER2LMNANPSR1 | |
| SCHEMBL24861821 | 0.90 | PTGER4 (0.76) | PTGER4PTGER2LMNANPSR1 | |
| SCHEMBL28709433 | 0.90 | PTGER4 (0.73) | PTGER4PTGER2LMNANPSR1POLB | |
| SCHEMBL24861725 | 0.86 | PTGER4 (0.65) | PTGER4PTGER2LMNANPSR1 | |
| SCHEMBL28702068 | 0.86 | PTGER4 (0.65) | PTGER4PTGER2LMNANPSR1 | |
| SCHEMBL881390 | 0.85 | PTGER4 (0.84) | PTGER4PTGER2LMNANPSR1 | |
| SCHEMBL24861726 | 0.85 | PTGER4 (0.60) | PTGER4PTGER2LMNANPSR1POLB | |
| SCHEMBL28709264 | 0.83 | PTGER4 (0.59) | PTGER4PTGER2LMNANPSR1POLB | |
| SCHEMBL24861927 | 0.83 | PTGER4 (0.89) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354585-A | Synthesis of novel EP4 antagonists and their use in cancer and inflammation | 湖北生物医药产业技术研究院有限公司 | 2021-09-07 | — | — | CN | disclosed |