Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.59 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24861730 | 0.90 | PTGER4 (0.72) | PTGER4PTGER2LMNANPSR1PHGDH | |
| SCHEMBL24861806 | 0.90 | PTGER4 (0.72) | PTGER4PTGER2LMNANPSR1PHGDH | |
| SCHEMBL24861973 | 0.86 | PTGER4 (0.61) | PTGER4PTGER2LMNANPSR1L3MBTL1 | |
| SCHEMBL24861972 | 0.86 | PTGER4 (0.61) | PTGER4PTGER2LMNANPSR1L3MBTL1 | |
| SCHEMBL24861731 | 0.84 | PTGER4 (0.57) | PTGER4PTGER2LMNANPSR1L3MBTL1 | |
| SCHEMBL26417363 | 0.83 | PTGER4 (0.72) | PTGER4PTGER2PHGDH | |
| SCHEMBL28702069 | 0.83 | PTGER4 (0.64) | PTGER4PTGER2LMNANPSR1POLB | |
| SCHEMBL26417331 | 0.80 | PTGER4 (0.72) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861880 | 0.80 | PTGER4 (0.72) | PTGER4PTGER2PHGDH | |
| SCHEMBL26416555 | 0.80 | PTGER4 (0.62) | PTGER4PTGER2CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354585-A | Synthesis of novel EP4 antagonists and their use in cancer and inflammation | 湖北生物医药产业技术研究院有限公司 | 2021-09-07 | — | — | CN | disclosed |