Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 9/20 | 0.51 |
| ▸ | CKS1B | P61024 | 2/20 | 0.50 |
| ▸ | SKP1 | P63208 | 2/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462137 | 0.85 | RET (0.54) | PGK1RETCKS1BSKP1SKP2 | |
| SCHEMBL31071888 | 0.85 | RET (0.54) | PGK1RETCKS1BSKP1SKP2 | |
| SCHEMBL28936733 | 0.84 | HDAC1 (0.47) | PGK1RETGPR119 | |
| SCHEMBL31143999 | 0.82 | RET (0.41) | PGK1RET | |
| SCHEMBL28711627 | 0.82 | RET (0.41) | PGK1RET | |
| SCHEMBL23107933 | 0.82 | GBA1 (0.58) | CKS1BSKP1SKP2GBA1POLB | |
| SCHEMBL28711629 | 0.82 | RET (0.43) | PGK1RET | |
| SCHEMBL28715860 | 0.80 | RET (0.52) | RETCKS1BSKP1SKP2 | |
| SCHEMBL31071901 | 0.78 | RET (0.71) | RET | |
| SCHEMBL31071882 | 0.78 | RET (0.53) | RETCKS1BSKP1SKP2WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461670-A | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |