Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 4/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 8/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 8/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143941 | 0.86 | RET (0.55) | HDAC1RETJAK1 | |
| SCHEMBL28703261 | 0.84 | PGK1 (0.54) | RETPGK1GPR119 | |
| SCHEMBL23878889 | 0.83 | JAK1 (0.49) | HDAC1KCNK3KCNK9JAK1GPR119 | |
| SCHEMBL30227536 | 0.83 | JAK1 (0.49) | HDAC1KCNK3KCNK9JAK1GPR119 | |
| SCHEMBL31071776 | 0.81 | RET (0.55) | HDAC1RETKCNK3KCNK9 | |
| SCHEMBL28715860 | 0.80 | RET (0.52) | RET | |
| SCHEMBL31143999 | 0.78 | RET (0.41) | RETPGK1 | |
| SCHEMBL28711627 | 0.78 | RET (0.41) | RETPGK1 | |
| SCHEMBL28711629 | 0.78 | RET (0.43) | RETPGK1 | |
| SCHEMBL21262007 | 0.76 | HDAC1 (0.59) | HDAC1RETKCNK3KCNK9JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461670-B | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-113461670-A | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |