Etocarlide

Etocarlide

SCHEMBL2870335

CCOc1ccc(NC(=S)Nc2ccc(OCC)cc2)cc1.C[PH](C)(C)Cc1ccccc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.68
LMNA P02545 4/20 0.62
GAA P10253 3/20 0.62
MAPK1 P28482 2/20 0.60
KMT2A Q03164 3/20 0.59
MEN1 O00255 2/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2C19 P33261 1/20 0.59
ALDH1A1 P00352 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
NPC1 O15118 1/20 0.56
HPGD P15428 1/20 0.56
RAB9A P51151 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
KDM4E B2RXH2 1/20 0.55
RECQL P46063 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etocarlide SCHEMBL7877294 0.87 MAPT (0.64) MAPTLMNAGAAMAPK1KMT2A
SCHEMBL12443334 0.85 MAPT (0.86) MAPTLMNAGAAMAPK1KMT2A
Etocarlide SCHEMBL5832118 0.84 MAPT (0.96) MAPTLMNAGAAKMT2AMEN1
Etocarlide SCHEMBL7877205 0.83 MAPT (0.71) MAPTLMNAGAAMAPK1KMT2A
Etocarlide SCHEMBL7871203 0.83 MAPT (0.71) MAPTLMNAGAAMAPK1KMT2A
Etocarlide SCHEMBL7872876 0.83 MAPT (0.71) MAPTLMNAGAAMAPK1KMT2A
Etocarlide SCHEMBL11706519 0.82 MAPT (0.69) MAPTLMNAGAAMAPK1KMT2A
Etocarlide SCHEMBL103618 0.82 MAPT (1.00) MAPTLMNAGAAKMT2AMEN1
Etocarlide SCHEMBL9263 0.82 MAPT (1.00) MAPTLMNAGAAKMT2AMEN1
Etocarlide SCHEMBL2857287 0.82 MAPT (0.73) MAPTLMNAGAAMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7842843-B2 Mixture containing 1,3-butadiene and process for producing the same KURARAY CO., LTD. (JP) 2010-11-30 US disclosed
US-7728180-B2 Method for producing ethers KURARAY CO., LTD. (JP) 2010-06-01 US disclosed
US-20080262272-A1 Method For Producing Ethers KURARAY CO., LTD. (JP) 2008-10-23 US disclosed
EP-1795578-A2 Mixture containing 1, 3-Butadiene and process for producing the same Kuraray Co., Ltd. (JP) 2007-06-13 EP disclosed
US-20070123738-A1 MIXTURE CONTAINING 1,3-BUTADIENE AND PROCESS FOR PRODUCING THE SAME KURARAY CO., LTD (JP) 2007-05-31 US disclosed
EP-1760061-A1 METHOD FOR PRODUCING ETHERS KURARAY CO., LTD. (JP) 2007-03-07 EP disclosed
US-6506838-B1 Comprising a linear polymer of oxymethylene repeat units, blocked at one end by at least one terminal group selected from the group consisting of an alkylene oxide as an adduct to alcohol and an alkylene oxide as an adduct to carboxylic acid ASAHI KASEI KABUSHIKI KAISHA (JP) 2003-01-14 US disclosed
EP-0429672-B1 ACETAL COPOLYMER AND METHOD OF PRODUCING THE SAME ASAHI CHEMICAL IND (JP) 1996-03-27 EP disclosed
EP-0474875-B1 THERMOPLASTIC GRAFT COPOLYMER AND PRODUCTION THEREOF ASAHI CHEMICAL IND (JP) 1995-11-15 EP disclosed
EP-0427874-B1 POLYACETAL COPOLYMER AND COMPOSITION THEREOF ASAHI CHEMICAL IND (JP) 1995-09-06 EP disclosed
US-5306769-A Graft copolymerization with particulate crosslinked vinyl monomer units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-04-26 US disclosed
US-5294670-A Copolymer with addition polymer, engineering resin, surface is easy to print and coat ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-03-15 US disclosed
US-5206325-A Mono- or polysaccharide grafted onto acetal resin ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-04-27 US disclosed
EP-0474875-A1 THERMOPLASTIC GRAFT COPOLYMER AND PRODUCTION THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-03-18 EP disclosed
EP-0429672-A1 ACETAL COPOLYMER AND METHOD OF PRODUCING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-06-05 EP disclosed
EP-0427874-A1 POLYACETAL COPOLYMER AND COMPOSITION THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-05-22 EP disclosed
US-4535127-A Polyacetal copolymers and process for production thereof ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-08-13 US disclosed
US-4380620-A ANIONIC POLYMERIZATION CATALYSTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-04-19 US disclosed
US-4377667-A ENCAPPING WITH AN ALKYLENE OXIDE ADDUCT OF AN ALCOHOL OR CARBOXYLIC ACID ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070123738-A1 MIXTURE CONTAINING 1,3-BUTADIENE AND PROCESS FOR PRODUCING THE SAME TELO2, MSMO1, HBG1 MAPT 1584/4885LMNA 169/4885GAA 4417/4885
US-20080262272-A1 Method For Producing Ethers TELO2, PDS5A, TERT MAPT 3987/4885LMNA 1009/4885GAA 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.