Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL2870352

C[O-].c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.43
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
TSHR P16473 5/20 0.37
ACHE P22303 2/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
TDP1 Q9NUW8 2/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MGLL Q99685 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
DPP4 P27487 2/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraphenylphosphonium SCHEMBL29362652 0.89 HIF1A (0.50) HIF1ATSHRACHELMNAALOX12
Tetraphenylphosphonium SCHEMBL126056 0.86 HIF1A (0.47) HIF1ATSHRACHELMNAALOX12
Tetraphenylphosphonium SCHEMBL30623276 0.86 HIF1A (0.47) HIF1ATSHRACHELMNAALOX12
Tetraphenylphosphonium SCHEMBL585136 0.86 HIF1A (0.47) HIF1ATSHRACHELMNAALOX12
Tetraphenylphosphonium SCHEMBL19921940 0.86 HIF1A (0.47) HIF1AMAOAMAOBTSHRACHE
Tetraphenylphosphonium SCHEMBL108817 0.86 HIF1A (0.47) HIF1ATSHRACHELMNAALOX12
Tetraphenylphosphonium SCHEMBL158514 0.86 HIF1A (0.47) HIF1ATSHRACHELMNAALOX12
Tetraphenylphosphonium SCHEMBL30168547 0.86 HIF1A (0.47) HIF1ATSHRACHELMNAALOX12
Tetraphenylphosphonium SCHEMBL9638111 0.86 HIF1A (0.47) HIF1ATSHRACHELMNAALOX12
Tetraphenylphosphonium SCHEMBL17818165 0.86 HIF1A (0.47) HIF1ATSHRACHELMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed
US-7842843-B2 Mixture containing 1,3-butadiene and process for producing the same KURARAY CO., LTD. (JP) 2010-11-30 US disclosed
US-7728180-B2 Method for producing ethers KURARAY CO., LTD. (JP) 2010-06-01 US disclosed
US-20080262272-A1 Method For Producing Ethers KURARAY CO., LTD. (JP) 2008-10-23 US disclosed
EP-1795578-A2 Mixture containing 1, 3-Butadiene and process for producing the same Kuraray Co., Ltd. (JP) 2007-06-13 EP disclosed
US-20070123738-A1 MIXTURE CONTAINING 1,3-BUTADIENE AND PROCESS FOR PRODUCING THE SAME KURARAY CO., LTD (JP) 2007-05-31 US disclosed
EP-1760061-A1 METHOD FOR PRODUCING ETHERS KURARAY CO., LTD. (JP) 2007-03-07 EP disclosed
US-6762259-B2 ACCURATE MOLECULAR WEIGHT CONTROL; POLYMERIZATION OF POLAR UNSATURATED MONOMERS IN PRESENCE OF HYDROXYCARBONYL COMPOUND AND ORGANIC OXYSALT CATALYST MITSUI CHEMICALS, INC. (JP) 2004-07-13 US disclosed
US-20030023003-A1 Process for the production of living (co)polymers and use of the (co)polymers MITSUI CHEMICALS, INC. (JP) 2003-01-30 US disclosed
EP-1266910-A1 PROCESS FOR THE PRODUCTION OF LIVING (CO)POLYMERS AND USE OF THE (CO)POLYMERS Mitsui Chemicals, Inc. (JP) 2002-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070123738-A1 MIXTURE CONTAINING 1,3-BUTADIENE AND PROCESS FOR PRODUCING THE SAME TELO2, MSMO1, HBG1 HIF1A 3766/4885MAOA 4643/4885MAOB 4559/4885
US-20080262272-A1 Method For Producing Ethers TELO2, PDS5A, TERT HIF1A 1391/4885MAOA 4544/4885MAOB 4049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.