⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670759 | 0.74 | — | — | |
| SCHEMBL28693634 | 0.67 | — | — | |
| SCHEMBL28791654 | 0.65 | — | — | |
| SCHEMBL16962385 | 0.62 | — | — | |
| SCHEMBL27422026 | 0.61 | MEN1 (0.32) | — | |
| SCHEMBL2067207 | 0.59 | — | — | |
| SCHEMBL29062267 | 0.57 | AURKA (0.31) | — | |
| SCHEMBL6535525 | 0.55 | — | — | |
| SCHEMBL15200783 | 0.55 | — | — | |
| SCHEMBL11464971 | 0.55 | MEN1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437105-A | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-109071504-B | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2022-03-08 | — | — | CN | disclosed |