Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11463871 | 0.89 | RXRB (0.41) | MEN1KMT2AGABRA1GABRB2KIF11 | |
| SCHEMBL28756105 | 0.83 | MEN1 (0.37) | MEN1KMT2AKIF11PRSS1ACR | |
| SCHEMBL80101 | 0.81 | MEN1 (0.66) | MEN1KMT2AKIF11RXRBRXRA | |
| SCHEMBL14488840 | 0.81 | CYP3A4 (0.47) | MEN1KMT2AGABRA1GABRB2RXRB | |
| SCHEMBL14220011 | 0.79 | GABRA1 (0.43) | MEN1KMT2AGABRA1GABRB2RXRB | |
| SCHEMBL27468878 | 0.79 | KIF11 (0.59) | MEN1KMT2AKIF11PRSS1ACR | |
| SCHEMBL377025 | 0.77 | MAPT (0.42) | MEN1KMT2AGABRA1GABRB2RXRB | |
| SCHEMBL77964 | 0.76 | GABRA1 (0.40) | MEN1KMT2AGABRA1GABRB2RXRB | |
| SCHEMBL1790890 | 0.76 | ELANE (0.53) | MEN1KMT2AGABRA1GABRB2RXRB | |
| SCHEMBL150571 | 0.76 | VCAM1 (0.39) | MEN1KMT2AGABRA1GABRB2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226377-A | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2021-08-06 | — | — | CN | disclosed |
| US-4226883-A | Carbamate derivatives and method for manufacture thereof | YAMAMOTO IZURU | 1980-10-07 | — | — | US | disclosed |