Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28710514 | 0.79 | HPGDS (0.55) | NOTUMTSHRSMN1; SMN2LMNAPOLB | |
| SCHEMBL28026195 | 0.78 | CYP2C19 (0.59) | NOTUMTSHRSMN1; SMN2LMNAPOLB | |
| SCHEMBL28706161 | 0.76 | HSD17B10 (0.43) | NOTUMTSHRSMN1; SMN2LMNAMEN1 | |
| SCHEMBL16136292 | 0.74 | GFER (0.46) | NOTUMTSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL3037128 | 0.73 | MAPT (0.46) | NOTUMTSHRSMN1; SMN2LMNAPOLB | |
| SCHEMBL19111415 | 0.72 | KDM4E (0.44) | NOTUMTSHRSMN1; SMN2LMNAPOLB | |
| SCHEMBL16133641 | 0.71 | MAPT (0.46) | NOTUMTSHRSMN1; SMN2LMNAPOLB | |
| SCHEMBL9638903 | 0.71 | AR (0.43) | NOTUMTSHRSMN1; SMN2LMNAPOLB | |
| SCHEMBL1713531 | 0.70 | SMN1; SMN2 (0.55) | NOTUMTSHRSMN1; SMN2LMNAPOLB | |
| SCHEMBL4418297 | 0.70 | HPGDS (0.51) | NOTUMTSHRSMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230522-A | Imidazole-2-carboxylic acid metal beta-lactamase inhibitor and preparation method and application thereof | 四川大学 | 2022-03-25 | — | — | CN | disclosed |