Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977559 | 0.87 | ALDH1A1 (0.78) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL28696410 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL28700535 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL6527811 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL10367084 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2605690 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2858127 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL27632186 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL1063935 | 0.84 | ALDH1A1 (0.73) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2860213 | 0.84 | KDM4E (0.73) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942567-B | 1,3,4-oxa (thia) diazolyl imidazole compound and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-109942567-A | A kind of 1,3,4- dislikes the glyoxaline compound and its preparation method and application of (thiophene) di azoly | 贵州大学 | 2019-06-28 | — | — | CN | disclosed |