SCHEMBL2870547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2864411	0.87	MAPK10 (0.46)	MAPK10SIRT2SIRT1KDRAURKA
	SCHEMBL13198310	0.87	MAPK10 (0.47)	RAB9AL3MBTL1MAPK10PIP5K1CSIRT2
	SCHEMBL4337567	0.87	MAPK10 (0.47)	RAB9AL3MBTL1MAPK10PIP5K1CSIRT2
	SCHEMBL2862938	0.86	MAPK10 (0.50)	RAB9AL3MBTL1MAPK10PIP5K1CSIRT2
	SCHEMBL2862326	0.85	KDM4E (0.46)	MAPK10SIRT2SIRT1KDRCHEK1
	SCHEMBL2864604	0.83	RAB9A (0.54)	RAB9AL3MBTL1SMN1; SMN2KDRCHEK1
	SCHEMBL4338881	0.82	KDM4E (0.53)	RAB9AMAPK10SMN1; SMN2ALDH1A1
	SCHEMBL2861021	0.82	PIP5K1C (0.46)	RAB9AL3MBTL1MAPK10PIP5K1CSIRT2
	SCHEMBL4336833	0.81	MAPK10 (0.40)	RAB9AMAPK10SIRT2SIRT1MAPKAPK2
	SCHEMBL4329239	0.81	MAPK1 (0.45)	MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.