Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706177 | 1.00 | TACR1 (0.37) | TACR1MEN1KMT2ATDP1ADRA1D | |
| SCHEMBL29633507 | 0.90 | MEN1 (0.36) | TACR1MEN1KMT2ATDP1ADRA1D | |
| Hydrochloric Acid SCHEMBL29633556 | 0.82 | KMT2A (0.43) | TACR1MEN1KMT2ATDP1ADRA1D | |
| SCHEMBL24489021 | 0.82 | TDP1 (0.39) | TACR1MEN1KMT2ATDP1HTR1A | |
| SCHEMBL28715431 | 0.80 | HTT (0.38) | ACHELMNASMN1; SMN2 | |
| SCHEMBL24489000 | 0.80 | HTT (0.38) | ACHELMNASMN1; SMN2 | |
| SCHEMBL22945517 | 0.78 | CTSB (0.37) | TACR1SMN1; SMN2KDM4EPOLBALDH1A1 | |
| SCHEMBL28700396 | 0.75 | KMT2A (0.41) | MEN1KMT2ATDP1ADRA1DADRA1A | |
| SCHEMBL28700397 | 0.75 | KMT2A (0.41) | MEN1KMT2ATDP1ADRA1DADRA1A | |
| SCHEMBL24488960 | 0.73 | LPAR1 (0.42) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |