Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134430 | 0.83 | MEN1 (0.58) | POLBMEN1KMT2AMAPTKDM4E | |
| SCHEMBL4897413 | 0.83 | MEN1 (0.58) | POLBMEN1KMT2AMAPTKDM4E | |
| SCHEMBL21225837 | 0.80 | KMT2A (0.54) | POLBMEN1KMT2AMAPTKDM4E | |
| SCHEMBL14809963 | 0.77 | POLB (0.51) | POLBMEN1KMT2AMAPTKDM4E | |
| SCHEMBL20601872 | 0.76 | POLB (0.54) | POLBMEN1KMT2AMAPTKDM4E | |
| Fluroxypyr SCHEMBL21173647 | 0.73 | TDP1 (0.61) | MEN1KMT2AMAPTTSHR | |
| SCHEMBL28921743 | 0.73 | MEN1 (0.50) | POLBMEN1KMT2AMAPTKDM4E | |
| Fluroxypyr SCHEMBL30612286 | 0.69 | TDP1 (0.34) | KMT2AKDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL10165416 | 0.68 | GAA (0.51) | POLBMEN1KMT2AMAPTHPGD | |
| SCHEMBL10857636 | 0.68 | NOTUM (0.70) | MEN1KMT2AMAPTNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997757-B | Isocyanate-functional silicone-polyether copolymers, silicone-polyether-urethane copolymers formed therewith, sealants including the same, and related methods | 美国陶氏有机硅公司 | 2022-03-08 | — | — | CN | disclosed |