⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844336 | 0.89 | ALDH1A1 (0.38) | — | |
| SCHEMBL9260314 | 0.88 | TSHR (0.32) | — | |
| SCHEMBL78112 | 0.85 | TSHR (0.54) | — | |
| Tetrahydrothiophene SCHEMBL27777466 | 0.84 | — | — | |
| Thiophene SCHEMBL27873700 | 0.84 | — | — | |
| SCHEMBL444299 | 0.83 | TSHR (0.46) | — | |
| SCHEMBL1579394 | 0.83 | — | — | |
| SCHEMBL269289 | 0.83 | — | — | |
| SCHEMBL11765764 | 0.82 | TSHR (0.39) | — | |
| SCHEMBL8193261 | 0.82 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567080-A | Environment-friendly odor-free asphalt mixture and preparation method thereof | 山东阳光沥青有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-114573283-B | Environment-friendly odorless asphalt mixture and preparation method thereof | 湖南路桥建设集团有限责任公司 | 2022-07-19 | — | — | CN | claimed |
| CN-114573283-A | Environment-friendly odorless asphalt mixture and preparation method thereof | 湖南路桥建设集团有限责任公司 | 2022-06-03 | — | — | CN | claimed |
| CN-112047964-A | Preparation method and application of Grignard reagent | 宋喂 | 2020-12-08 | — | — | CN | claimed |
| CN-111747685-A | Environment-friendly odorless asphalt mixture and preparation method thereof | 上海佳砼新材料科技发展有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-111607243-A | Environment-friendly odorless asphalt composition and preparation method thereof | 上海佳砼新材料科技发展有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-106795174-B | Antiviral active diazacyclospirodiketopiperazine alkaloid derivative and preparation method thereof | 扬州蓝色生物医药科技有限公司 | 2020-04-28 | — | — | CN | claimed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | claimed |
| CN-117567080-A | Environment-friendly odor-free asphalt mixture and preparation method thereof | 山东阳光沥青有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-114573283-B | Environment-friendly odorless asphalt mixture and preparation method thereof | 湖南路桥建设集团有限责任公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-114573283-A | Environment-friendly odorless asphalt mixture and preparation method thereof | 湖南路桥建设集团有限责任公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-112047964-A | Preparation method and application of Grignard reagent | 宋喂 | 2020-12-08 | — | — | CN | disclosed |
| CN-111747685-A | Environment-friendly odorless asphalt mixture and preparation method thereof | 上海佳砼新材料科技发展有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-111607243-A | Environment-friendly odorless asphalt composition and preparation method thereof | 上海佳砼新材料科技发展有限公司 | 2020-09-01 | — | — | CN | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4764367-A | Use of C8 -t-alkanols and C5 -C11 -omega-alken-1-ols in attracting insects | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1988-08-16 | — | — | US | disclosed |
| US-4288454-A | Antiviral 1-adamantyl-3-(phenylsulfonyl)thioureas | HOFFMAN-LA ROCHE INC. (US) | 1981-09-08 | — | — | US | disclosed |
| US-4096145-A | DYES FOR RESINS AND POLYESTER TEXTILES | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-3950321-A | POLYESTERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
| US-3948991-A | Cyclic aldol condensation process and catalyst regeneration procedure | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1976-04-06 | — | — | US | disclosed |