Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 13/20 | 0.61 |
| ▸ | NTRK2 | Q16620 | 11/20 | 0.61 |
| ▸ | NTRK3 | Q16288 | 10/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | KIT | P10721 | 3/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 6/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | PAK4 | O96013 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706610 | 1.00 | NTRK1 (0.61) | NTRK1NTRK2NTRK3CHEK1CSF1R | |
| SCHEMBL30792166 | 1.00 | NTRK1 (0.61) | NTRK1NTRK2NTRK3CHEK1CSF1R | |
| SCHEMBL29387738 | 1.00 | NTRK1 (0.61) | NTRK1NTRK2NTRK3CHEK1CSF1R | |
| SCHEMBL30792139 | 0.93 | NTRK1 (0.59) | NTRK1NTRK2NTRK3CHEK1CSF1R | |
| SCHEMBL28697259 | 0.93 | NTRK1 (0.59) | NTRK1NTRK2NTRK3CHEK1CSF1R | |
| SCHEMBL29390083 | 0.93 | NTRK1 (0.59) | NTRK1NTRK2NTRK3CHEK1CSF1R | |
| SCHEMBL28697258 | 0.93 | NTRK1 (0.59) | NTRK1NTRK2NTRK3CHEK1CSF1R | |
| SCHEMBL28684861 | 0.91 | NTRK1 (0.64) | NTRK1NTRK2NTRK3CHEK1CSF1R | |
| SCHEMBL28684857 | 0.91 | NTRK1 (0.64) | NTRK1NTRK2NTRK3CHEK1CSF1R | |
| SCHEMBL28686141 | 0.89 | NTRK1 (0.58) | NTRK1NTRK2NTRK3CHEK1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-A | Indazole compound and medicinal composition and application thereof | 暨南大学 | 2022-02-18 | — | — | CN | disclosed |