Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.63 |
| ▸ | CTSL | P07711 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513049 | 1.00 | CTSV (0.63) | CTSVCTSLBCHELOXL2MTNR1A | |
| SCHEMBL31454125 | 1.00 | CTSV (0.63) | CTSVCTSLBCHELOXL2MTNR1A | |
| SCHEMBL3696629 | 1.00 | CTSV (0.63) | CTSVCTSLBCHELOXL2MTNR1A | |
| SCHEMBL10513013 | 1.00 | CTSV (0.63) | CTSVCTSLBCHELOXL2MTNR1A | |
| SCHEMBL31041747 | 1.00 | CTSV (0.63) | CTSVCTSLBCHELOXL2MTNR1A | |
| SCHEMBL3702698 | 1.00 | CTSV (0.63) | CTSVCTSLBCHELOXL2MTNR1A | |
| SCHEMBL11415263 | 1.00 | CTSV (0.63) | CTSVCTSLBCHELOXL2MTNR1A | |
| Methane SCHEMBL27817441 | 0.98 | CTSV (0.61) | CTSVCTSLBCHELOXL2MTNR1A | |
| SCHEMBL28774442 | 0.98 | CTSV (0.61) | CTSVCTSLBCHELOXL2MTNR1A | |
| SCHEMBL30382957 | 0.98 | CTSV (0.60) | CTSVCTSLBCHELOXL2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198888-B | 2,3a bis- substitutes 3H-pyrazolo [1,5 a] indoles 4 (3aH) ketone derivatives and its synthetic method | 湘潭大学 | 2018-03-06 | — | — | CN | claimed |
| CN-105198888-A | 2,3a-disubstituted-3H-pyrazole[1,5-a]indole-4(3aH)-ketone, derivative and synthetic method of 2,3a-disubstituted-3H-pyrazole[1,5-a]indole-4(3aH)-ketone and derivative | UNIV XIANGTAN | 2015-12-30 | — | — | CN | claimed |
| JP-3193762-A | — | — | None | — | — | JP | disclosed |
| JP-3193762-A | — | — | None | — | — | JP | disclosed |
| CN-118420511-A | Synthesis method of 2-alkyl indole | 南京工业大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-112881577-B | Liquid chromatography-mass spectrometry-based molecular characterization method for nitrogen-containing compounds in petroleum fractions | 中国科学院大连化学物理研究所 | 2022-03-08 | — | — | CN | disclosed |
| CN-112881577-A | Liquid chromatography-mass spectrometry-based molecular characterization method for nitrogen-containing compounds in petroleum fractions | 中国科学院大连化学物理研究所 | 2021-06-01 | — | — | CN | disclosed |
| CN-106243327-B | Union II indole dione class D-A-D type polymer electrochromic materials and preparation method thereof | 江西科技师范大学 | 2018-11-06 | — | — | CN | disclosed |
| CN-105198888-B | 2,3a bis- substitutes 3H-pyrazolo [1,5 a] indoles 4 (3aH) ketone derivatives and its synthetic method | 湘潭大学 | 2018-03-06 | — | — | CN | disclosed |
| US-9464048-B2 | 5-oxo-ETE receptor antagonist compounds | FLORIDA INSTITUTE OF TECHNOLOGY (US) | 2016-10-11 | — | — | US | disclosed |
| CN-105198888-A | 2,3a-disubstituted-3H-pyrazole[1,5-a]indole-4(3aH)-ketone, derivative and synthetic method of 2,3a-disubstituted-3H-pyrazole[1,5-a]indole-4(3aH)-ketone and derivative | UNIV XIANGTAN | 2015-12-30 | — | — | CN | disclosed |
| US-20080039625-A1 | Screening Methods | LAUTENS MARK | 2008-02-14 | — | — | US | disclosed |
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |
| EP-1817283-A1 | 2-SUBSTITUTED INDOLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | Lautens, Mark (CA) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006047888-A1 | 2-SUBSTITUTED INDOLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2006-05-11 | — | — | WO | disclosed |
| JP-H03193762-A | METHYLENE-CROSSLINKED INDOLYL ARYL METHANE COMPOUND | FUJI PHOTO FILM CO LTD | 1991-08-23 | — | — | JP | disclosed |
| JP-H03193762-A | METHYLENE-CROSSLINKED INDOLYL ARYL METHANE COMPOUND | FUJI PHOTO FILM CO LTD | 1991-08-23 | — | — | JP | disclosed |
| CN-85108623-A | Preparation has the novel method of the heterocycleamide of medical active | — | 1986-07-30 | — | — | CN | disclosed |
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039625-A1 | Screening Methods | CBR3, ZKSCAN2, CRBN | CTSV 1601/4885CTSL 1159/4885BCHE 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.