Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.61 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.43 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518749 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4527399 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4538834 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4539050 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4526591 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4521470 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4529975 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4539600 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4532688 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4528979 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3549 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043082-A2 | COMPOSITIONS AND METHODS TO IMPROVE RNA PROPERTIES USING BASE, PHOSPHODIESTER LINKAGE, SUGAR BACKBONE, AND CAP MODIFICATIONS | THE BROAD INSTITUTE, INC. (US) | 2025-02-27 | — | — | WO | claimed |
| EP-2895607-B1 | DOUBLE-STRANDED OLIGONUCLEOTIDE MOLECULES TO DDIT4 AND METHODS OF USE THEREOF | QUARK PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | claimed |
| CN-106701758-B | Modulation of HSP47 expression | 日东电工株式会社 | 2020-02-07 | — | — | CN | claimed |
| CN-109852669-A | A kind of method of acridinium ester label nucleic acid | 南京航思生物科技有限公司 | 2019-06-07 | — | — | CN | claimed |
| EP-3434773-A2 | MODULATION OF HSP47 EXPRESSION | NITTO DENKO CORPORATION (JP) | 2019-01-30 | — | — | EP | claimed |
| US-10093923-B2 | Modulation of HSP47 expression | NITTO DENKO CORPORATION (JP) | 2018-10-09 | — | — | US | claimed |
| US-20180179541-A1 | Modified L-Nucleic Acid | NOXXON PHARMA AG (DE) | 2018-06-28 | — | — | US | claimed |
| US-9611474-B2 | Double-stranded oligonucleotide molecules to DDIT4 and methods of use thereof | QUARK PHARMACEUTICALS, INC. (US) | 2017-04-04 | — | — | US | claimed |
| US-20160376594-A1 | Modified L-Nucleic Acid | NOXXON PHARMA AG (DE) | 2016-12-29 | — | — | US | claimed |
| US-9328347-B2 | siRNA useful in the treatment of flavivirus infection | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2016-05-03 | — | — | US | claimed |
| EP-1071753-A2 | NUCLEIC ACID MOLECULES WITH NOVEL CHEMICAL COMPOSITIONS CAPABLE OF MODULATING GENE EXPRESSION | RIBOZYME PHARMACEUTICALS, INC. (US) | 2001-01-31 | — | — | EP | claimed |
| WO-2000017346-A2 | HAIRPIN HYBRIDIZER MOLECULES FOR MODULATION OF GENE EXPRESSION | RIBOZYME PHARMACEUTICALS, INC. (US) | 2000-03-30 | — | — | WO | claimed |
| WO-2000004141-A2 | USE OF NUCLEIC ACID MOLECULES AS ANTIVIRAL AGENTS | RIBOZYME PHARMACEUTICALS, INC. (US) | 2000-01-27 | — | — | WO | claimed |
| US-5998203-A | PARTICULARLY USEFUL FOR ENZYMATIC CLEAVAGE OF RNA OR SINGLE-STRANDED DNA. | RIBOZYME PHARMACEUTICALS, INC. (US) | 1999-12-07 | — | — | US | claimed |
| WO-1999054459-A2 | NUCLEIC ACID MOLECULES WITH NOVEL CHEMICAL COMPOSITIONS CAPABLE OF MODULATING GENE EXPRESSION | RIBOZYME PHARMACEUTICALS, INC. (US) | 1999-10-28 | — | — | WO | claimed |
| EP-0886641-A2 | SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1998-12-30 | — | — | EP | claimed |
| WO-1997026270-A2 | SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1997-07-24 | — | — | WO | claimed |
| US-5633111-A | Photoresist composition and article containing 1,2-quinonediazide and an organic phosphorous acid compound | FUJI PHOTO FILM CO., LTD. (JP) | 1997-05-27 | — | — | US | claimed |
| US-5254430-A | Lithographic printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-19 | — | — | US | claimed |
| US-5230988-A | Image exposure of plates of aluminum with phosphate or phosphonate compounds and basic compounds | FUJI PHOTO FILM CO., LTD. (JP) | 1993-07-27 | — | — | US | claimed |