Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.61 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.43 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527399 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4538834 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4539050 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4526591 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4521470 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL28707 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4529975 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4539600 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4532688 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 | |
| SCHEMBL4528979 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1FDPSITPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123516-A1 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-05-14 | — | — | US | disclosed |
| WO-2007019478-A2 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-02-15 | — | — | WO | disclosed |