Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL27494289 | 0.98 | HSD17B10 (0.57) | HSD17B10ALDH1A1SLC6A2HTR2BALOX12 | |
| Diphenylamine SCHEMBL28474170 | 0.98 | HSD17B10 (0.57) | HSD17B10ALDH1A1SLC6A2HTR2BALOX12 | |
| Diphenylamine SCHEMBL28124881 | 0.93 | HSD17B10 (0.52) | HSD17B10ALDH1A1SLC6A2HTR2BALOX12 | |
| SCHEMBL26322229 | 0.86 | HSD17B10 (0.54) | HSD17B10ALDH1A1SLC6A2HTR2BALOX12 | |
| SCHEMBL2165580 | 0.86 | CYP1A2 (0.60) | HSD17B10ALDH1A1SLC6A2HTR2BALOX12 | |
| Diphenylamine SCHEMBL28075674 | 0.85 | HSD17B10 (0.67) | HSD17B10ALDH1A1SLC6A2HTR2BALOX12 | |
| Fluorene SCHEMBL27485073 | 0.83 | MAOA (0.65) | HSD17B10ALDH1A1SLC6A2HTR2BTSHR | |
| Fluorene SCHEMBL14118022 | 0.83 | MAOA (0.65) | HSD17B10ALDH1A1TSHRMAPK1MAOA | |
| Fluorene SCHEMBL27934493 | 0.83 | MAOA (0.65) | HSD17B10ALDH1A1TSHRMAPK1MAOA | |
| SCHEMBL25458414 | 0.82 | CNR1 (0.53) | HSD17B10ALDH1A1SLC6A2HTR2BALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181127-B | Sulfur-containing fluorene diphenylamine, mercapto fluorene aromatic amine, and preparation methods and applications thereof | 深圳无限光能技术有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-114181127-A | Sulfur-containing fluorene diphenylamine and mercaptofluorene arylamine, and preparation method and application thereof | 清华大学 | 2022-03-15 | — | — | CN | disclosed |