Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | PROC | P04070 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500798 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL17028812 | 0.89 | F2 (0.46) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL9926718 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL1269634 | 0.83 | NQO2 (0.54) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL27944294 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL12922436 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL30407813 | 0.83 | NQO2 (0.54) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL15150307 | 0.81 | ALDH1A1 (0.48) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL6776686 | 0.81 | GAA (0.44) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 | |
| SCHEMBL15562826 | 0.81 | TSHR (0.41) | SMN1; SMN2HSD17B10ALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110128407-B | Preparation method of dabigatran etexilate key intermediate | 连云港恒运药业有限公司 | 2022-04-01 | — | — | CN | disclosed |