Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 0.74 |
| ▸ | MMP13 | P45452 | 20/20 | 0.74 |
| ▸ | MMP2 | P08253 | 2/20 | 0.74 |
| ▸ | MMP3 | P08254 | 2/20 | 0.74 |
| ▸ | MMP9 | P14780 | 2/20 | 0.74 |
| ▸ | MMP8 | P22894 | 2/20 | 0.74 |
| ▸ | MMP12 | P39900 | 1/20 | 0.65 |
| ▸ | MMP14 | P50281 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707435 | 0.87 | MMP1 (0.56) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6994722 | 0.85 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6996574 | 0.85 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6994719 | 0.85 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6962773 | 0.84 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL8496661 | 0.83 | MMP1 (0.74) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL8492413 | 0.83 | MMP1 (0.74) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6964194 | 0.82 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6960491 | 0.82 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6958565 | 0.81 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999578-B | Human monoclonal antibodies against EPHA4 and uses thereof | 美国政府(由卫生和人类服务部的部长所代表) | 2022-03-04 | — | — | CN | disclosed |