Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14129328 | 0.97 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL13799310 | 0.97 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL25533026 | 0.97 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL20573620 | 0.97 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL16408435 | 0.97 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL18530440 | 0.94 | HDAC8 (0.32) | HDAC8 | |
| SCHEMBL25272001 | 0.90 | HDAC8 (0.33) | HDAC8 | |
| SCHEMBL28497443 | 0.89 | HDAC8 (0.33) | HDAC8 | |
| SCHEMBL30864449 | 0.88 | — | — | |
| SCHEMBL31739294 | 0.87 | CES2 (0.35) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143961-B | Pyrrolo-pyridone bifunctional molecular compound based on VHL ligand-induced BET degradation | 江苏省中医药研究院 | 2022-03-29 | — | — | CN | disclosed |
| CN-110204543-B | Pyrrolopyridinone bifunctional molecular compound based on Cereblon ligand induced BET degradation | 江苏省中医药研究院 | 2022-03-29 | — | — | CN | disclosed |