Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30537737 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1GAATLR8CNR2 | |
| SCHEMBL17557973 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1GAATLR8CNR2 | |
| SCHEMBL28407056 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1GAATLR8CNR2 | |
| SCHEMBL28592388 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1GAATLR8CNR2 | |
| SCHEMBL29061701 | 0.77 | KDM4E (0.36) | KDM4EALDH1A1GAATLR8CNR2 | |
| SCHEMBL27845062 | 0.74 | PGR (0.36) | — | |
| SCHEMBL1988869 | 0.73 | TLR8 (0.34) | KDM4EALDH1A1GAATLR8CNR2 | |
| SCHEMBL832932 | 0.71 | SREBF2 (0.34) | KDM4EALDH1A1GAATLR8 | |
| SCHEMBL5149140 | 0.71 | ESR1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL27639543 | 0.69 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149405-B | Method for synthesizing aromatic thioether through aromatic exchange bimetallic catalysis and application thereof | 中国科学院大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-114149405-A | Method for synthesizing aromatic thioether through aromatic exchange bimetallic catalysis and application | 中国科学院大学 | 2022-03-08 | — | — | CN | disclosed |