Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | CALCRL | Q16602 | 5/20 | 0.35 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29997207 | 1.00 | CALCA (0.41) | CALCAALDH1A1SRD5A2KDM4EMAPT | |
| SCHEMBL30973608 | 0.85 | CALCRL (0.41) | CALCACALCRLRAMP1 | |
| SCHEMBL30973610 | 0.85 | CALCRL (0.41) | CALCACALCRLRAMP1 | |
| SCHEMBL29517935 | 0.85 | CALCRL (0.41) | CALCACALCRLRAMP1 | |
| Hydrochloric Acid SCHEMBL31126009 | 0.84 | CALCRL (0.40) | CALCACALCRLRAMP1 | |
| Hydrochloric Acid SCHEMBL29517767 | 0.84 | CALCRL (0.40) | CALCACALCRLRAMP1 | |
| Water SCHEMBL29517893 | 0.84 | CALCRL (0.40) | CALCACALCRLRAMP1 | |
| SCHEMBL7030609 | 0.79 | CALCRL (0.51) | CALCACALCRLRAMP1 | |
| SCHEMBL1815456 | 0.79 | CALCRL (0.51) | CALCACALCRLRAMP1 | |
| SCHEMBL29996226 | 0.79 | CALCRL (0.51) | CALCACALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114245798-A | CGRP antagonist compounds | 赫普泰雅治疗有限公司 | 2022-03-25 | — | — | CN | disclosed |