Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 9/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29837320 | 0.88 | KDR (0.49) | BRAFKDRFLT1AXL | |
| SCHEMBL2315935 | 0.88 | KDR (0.49) | BRAFKDRFLT1AXL | |
| SCHEMBL29837321 | 0.88 | KDR (0.49) | BRAFKDRFLT1AXL | |
| SCHEMBL28697205 | 0.87 | BRAF (0.40) | BRAFKDRFLT1AAK1LMNA | |
| SCHEMBL28690805 | 0.86 | KDR (0.41) | BRAFKDRFLT1 | |
| SCHEMBL28690910 | 0.85 | KDR (0.42) | BRAFKDRFLT1 | |
| SCHEMBL22919877 | 0.85 | KDR (0.47) | BRAFKDRFLT1 | |
| SCHEMBL28706557 | 0.85 | ABL1 (0.47) | BRAFKDRFLT1AXL | |
| SCHEMBL3751510 | 0.84 | BRAF (0.43) | BRAFKDRFLT1 | |
| SCHEMBL28684763 | 0.84 | KDR (0.40) | KDRFLT1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |