Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 6/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29544489 | 1.00 | DEGS1 (0.43) | DEGS1ABL1SLC2A1EP300HRH4 | |
| Trifluoroacetic Acid SCHEMBL18453329 | 0.89 | CHRNB2 (0.47) | HRH4HRH3 | |
| SCHEMBL18453953 | 0.88 | MAPT (0.44) | DEGS1ABL1EP300MAPTNPC1 | |
| Trifluoroacetic Acid SCHEMBL29544383 | 0.88 | AOC3 (0.44) | DEGS1ABL1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL18453954 | 0.88 | JAK2 (0.48) | DEGS1SLC2A1EP300MAPTNPC1 | |
| Trifluoroacetic Acid SCHEMBL18453971 | 0.88 | JAK2 (0.48) | DEGS1SLC2A1EP300MAPTNPC1 | |
| Trifluoroacetic Acid SCHEMBL18453160 | 0.88 | CDK6 (0.46) | DEGS1ABL1SLC2A1EP300HRH4 | |
| Trifluoroacetic Acid SCHEMBL18453319 | 0.88 | AOC3 (0.44) | DEGS1ABL1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL28705254 | 0.88 | AOC3 (0.44) | DEGS1ABL1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL18454041 | 0.87 | DEGS1 (0.47) | DEGS1SLC2A1HRH4DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269742-A | Derivatives of 4- (imidazo [1,2-a ] pyridin-3-yl) -N- (pyridinyl) pyrimidin-2-amines as therapeutic agents | 常州千红生化制药股份有限公司 | 2022-04-01 | — | — | CN | disclosed |