Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.67 |
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870853 | 1.00 | MCHR1 (0.68) | MCHR1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL2814883 | 0.93 | RAB9A (0.64) | MCHR1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL2812283 | 0.93 | RAB9A (0.64) | MCHR1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL2812279 | 0.93 | RAB9A (0.64) | MCHR1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL417284 | 0.87 | MCHR1 (0.72) | MCHR1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL417285 | 0.87 | MCHR1 (0.72) | MCHR1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL420200 | 0.87 | MCHR1 (0.69) | MCHR1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL420199 | 0.87 | MCHR1 (0.69) | MCHR1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL420113 | 0.84 | MCHR1 (0.51) | MCHR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL420114 | 0.84 | MCHR1 (0.51) | MCHR1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552199-B2 | Substituted indanes, method for the production thereof, and use thereof as drugs | SANOFI (FR) | 2013-10-08 | — | — | US | disclosed |
| EP-2396298-A1 | NOVEL SUBSTITUTED INDANES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS DRUGS | SANOFI (FR) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010092154-A1 | NOVEL SUBSTITUTED INDANES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS DRUGS | SANOFI-AVENTIS (FR) | 2010-08-19 | — | — | WO | disclosed |