Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.32 |
| ▸ | FEN1 | P39748 | 4/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103675 | 0.76 | ALOX5AP (0.41) | FFAR1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL20103177 | 0.68 | FFAR1 (0.43) | FFAR1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL21644913 | 0.68 | FFAR1 (0.43) | FFAR1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL20103176 | 0.68 | FFAR1 (0.43) | FFAR1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL20103485 | 0.65 | FFAR1 (0.42) | FFAR1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL20103605 | 0.64 | FFAR1 (0.40) | FFAR1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL16318672 | 0.60 | PDE2A (0.40) | FFAR1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL12192066 | 0.60 | FFAR1 (0.51) | FFAR1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL2317185 | 0.59 | FFAR1 (0.51) | FFAR1FFAR4 | |
| SCHEMBL2310827 | 0.59 | FFAR1 (0.51) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206874-A | Bicyclic heteroaryl compounds useful as IRAK4 inhibitors | 百时美施贵宝公司 | 2022-03-18 | — | — | CN | claimed |
| CN-114206874-A | Bicyclic heteroaryl compounds useful as IRAK4 inhibitors | 百时美施贵宝公司 | 2022-03-18 | — | — | CN | disclosed |