Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KLK7 | P49862 | 2/20 | 0.50 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28709128 | 1.00 | CNR2 (0.58) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL28785765 | 0.90 | HDAC4 (0.70) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL2841700 | 0.85 | HDAC3 (0.64) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL20490426 | 0.83 | HDAC3 (0.60) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL20490505 | 0.82 | HDAC3 (0.58) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL28709110 | 0.80 | ANPEP (0.46) | CNR2CNR1ALDH1A1NPSR1GPR88 | |
| SCHEMBL28710172 | 0.80 | ANPEP (0.46) | CNR2CNR1ALDH1A1NPSR1GPR88 | |
| SCHEMBL2843919 | 0.79 | MAPK1 (0.56) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL28934074 | 0.79 | HDAC3 (0.51) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL28934073 | 0.79 | HDAC3 (0.51) | CNR2CNR1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181116-B | D-amino acid derivative aminopeptidase N inhibitor, and preparation method and application thereof | 山东中医药大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114181116-A | D-amino acid derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2022-03-15 | — | — | CN | disclosed |