Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 4/20 | 0.47 |
| ▸ | ANPEP | P15144 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28934074 | 1.00 | HDAC3 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28709110 | 0.88 | ANPEP (0.46) | NPSR1MMP1ANPEPMMP3MMP13 | |
| SCHEMBL28710172 | 0.88 | ANPEP (0.46) | NPSR1MMP1ANPEPMMP3MMP13 | |
| SCHEMBL28700696 | 0.80 | CNR2 (0.48) | HDAC1HDAC7MMP1ANPEPMMP3 | |
| SCHEMBL28700697 | 0.80 | CNR2 (0.48) | HDAC1HDAC7MMP1ANPEPMMP3 | |
| SCHEMBL28709128 | 0.79 | CNR2 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28709129 | 0.79 | CNR2 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28933993 | 0.77 | ATM (0.54) | NPSR1CNR2GPR88ATMTP53 | |
| SCHEMBL7036247 | 0.74 | NPSR1 (0.69) | NPSR1ANPEPCNR2ATMCNR1 | |
| SCHEMBL28785765 | 0.73 | HDAC4 (0.70) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181116-B | D-amino acid derivative aminopeptidase N inhibitor, and preparation method and application thereof | 山东中医药大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114181116-A | D-amino acid derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2022-03-15 | — | — | CN | disclosed |