Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31291041 | 1.00 | PPARA (0.42) | PPARAGPR119USP30JAK2JAK1 | |
| SCHEMBL23761169 | 1.00 | PPARA (0.42) | PPARAGPR119USP30JAK2JAK1 | |
| SCHEMBL28700147 | 1.00 | PPARA (0.42) | PPARAGPR119USP30JAK2JAK1 | |
| SCHEMBL23761168 | 1.00 | PPARA (0.42) | PPARAGPR119USP30JAK2JAK1 | |
| SCHEMBL29257778 | 0.95 | PPARA (0.43) | PPARAGPR119NR1H2NR1H3MMP9 | |
| SCHEMBL29257781 | 0.95 | PPARA (0.43) | PPARAGPR119NR1H2NR1H3MMP9 | |
| SCHEMBL31588553 | 0.93 | GPR119 (0.40) | PPARAGPR119USP30JAK2JAK1 | |
| SCHEMBL25957354 | 0.92 | GPR119 (0.42) | PPARAGPR119JAK2JAK1STS | |
| SCHEMBL22764724 | 0.92 | GPR119 (0.46) | PPARAGPR119USP30JAK2JAK1 | |
| SCHEMBL28709765 | 0.92 | GPR119 (0.46) | PPARAGPR119USP30JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008021-A | Pyrrolidine compounds | 伊莱利利公司 | 2022-02-01 | — | — | CN | disclosed |