Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29449727 | 1.00 | TP53 (0.55) | TP53MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28700807 | 0.77 | KMT2A (0.55) | TP53MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29449739 | 0.77 | KMT2A (0.55) | TP53MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28694488 | 0.75 | KMT2A (0.58) | TP53MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28317879 | 0.74 | CYP2C9 (0.56) | TP53MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29449722 | 0.72 | TRIM24 (0.61) | KMT2AALDH1A1TRIM24NOTUMLMNA | |
| SCHEMBL28934090 | 0.72 | TRIM24 (0.61) | KMT2AALDH1A1TRIM24NOTUMLMNA | |
| SCHEMBL28710293 | 0.72 | KMT2A (0.55) | TP53MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28710339 | 0.72 | KMT2A (0.55) | TP53MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6273537 | 0.71 | NOTUM (0.57) | MEN1KMT2AALDH1A1MAPTNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218172-B | Method for preparing N-aryl sulfonamide from indoline and aryl sulfonamide | 常州大学 | 2022-03-22 | — | — | CN | disclosed |