Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30730949 | 0.78 | KMT2A (0.63) | NOTUMALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL6273233 | 0.78 | KMT2A (0.63) | NOTUMALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL6270911 | 0.77 | NOTUM (0.51) | NOTUMLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL30730960 | 0.73 | NOTUM (1.00) | NOTUMALDH1A1 | |
| SCHEMBL3895361 | 0.73 | NOTUM (1.00) | NOTUMALDH1A1 | |
| SCHEMBL12565602 | 0.71 | ALDH1A1 (0.50) | NOTUMALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL3427457 | 0.71 | ALDH1A1 (0.50) | NOTUMALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL29449727 | 0.71 | TP53 (0.55) | NOTUMALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL28710183 | 0.71 | TP53 (0.55) | NOTUMALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL29187823 | 0.71 | NOTUM (0.47) | NOTUMALDH1A1LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161418-B1 | 1-ACYL-7-NITROINDOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PHOTOCLEAVABLE PRECURSORS | MEDICAL RES COUNCIL (GB) | 2005-12-28 | — | — | EP | disclosed |
| US-6765014-B1 | DRUG DELIVERY OF NEUROACTIVE AMINO ACIDS OR METAL CHELATORS | MEDICAL RESEARCH COUNCIL (GB) | 2004-07-20 | — | — | US | disclosed |