Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24027178 | 0.71 | HTT (0.39) | ADORA3ADORA2AADORA1 | |
| SCHEMBL26195307 | 0.69 | ALDH1A1 (0.36) | KMT2A | |
| SCHEMBL20615682 | 0.68 | DPP4 (0.40) | ADORA3ADORA2AADORA1CTSDBACE1 | |
| SCHEMBL12197531 | 0.68 | MGAM (0.45) | KMT2A | |
| SCHEMBL18680934 | 0.67 | SCD (0.50) | ADORA3ADORA2AADORA1 | |
| SCHEMBL25005776 | 0.67 | ELANE (0.32) | NPC1 | |
| SCHEMBL12197486 | 0.66 | ALDH1A1 (0.60) | ADORA3ADORA2AADORA1CYP1A2KMT2A | |
| SCHEMBL12092341 | 0.64 | DPP4 (0.36) | ADORA3ADORA2AADORA1 | |
| SCHEMBL12196309 | 0.64 | GGPS1 (0.35) | ADORA2AADORA1 | |
| SCHEMBL16263166 | 0.64 | AR (0.41) | CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269755-A | 4,4A,5,7,8, 8A-hexapyrido [4,3-B ] [1,4] oxazin-3-one compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2022-04-01 | — | — | CN | disclosed |