Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936962 | 0.78 | CYP3A4 (0.33) | TSHRTDP1CYP3A4ATM | |
| SCHEMBL4763305 | 0.76 | TSHR (0.47) | TSHRTDP1L3MBTL1KDM4E | |
| SCHEMBL633254 | 0.74 | MAPT (0.50) | TSHRTDP1L3MBTL1KDM4E | |
| SCHEMBL3307290 | 0.73 | — | — | |
| SCHEMBL9935949 | 0.72 | TSHR (0.38) | TSHRTDP1L3MBTL1 | |
| SCHEMBL13141065 | 0.71 | TSHR (0.38) | TSHRKDM4E | |
| SCHEMBL8946551 | 0.71 | LMNA (0.53) | KDM4E | |
| SCHEMBL22355976 | 0.70 | — | — | |
| SCHEMBL12172802 | 0.69 | — | — | |
| SCHEMBL28591226 | 0.68 | CYP3A4 (0.70) | TSHRTDP1CYP3A4ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591223-A | Beta-lactamase inhibitor compounds | 恩塔西斯治疗有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-109715630-B | Beta-lactamase inhibitor compounds | 恩塔西斯治疗有限公司 | 2022-02-22 | — | — | CN | disclosed |