SCHEMBL28711966

SCHEMBL28711966

CCCC1(Br)C=CC(c2ccccc2)=CC1Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.33
KDM1A O60341 2/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28713494 0.76 KDM1A (0.33) HTTKDM1AMAOAMAOB
SCHEMBL28713519 0.74 HTT (0.35) HTT
SCHEMBL7786329 0.73 MMP2 (0.33) HTT
SCHEMBL28437265 0.73 MMP2 (0.33) HTT
Methane SCHEMBL27715684 0.71 HTT (0.30) HTT
SCHEMBL29055453 0.71 HTT (0.36) HTTKDM1AMAOAMAOB
SCHEMBL27795674 0.70 HTT (0.35) HTT
SCHEMBL27790664 0.69
SCHEMBL29055435 0.68 HTT (0.33) HTTKDM1AMAOAMAOB
SCHEMBL9842362 0.67 KDM1A (0.34) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109749755-B Liquid crystal compound and composition for improving environmental adaptability of liquid crystal material 西安近代化学研究所 2022-03-15 CN disclosed