SCHEMBL28711978

SCHEMBL28711978

OCCOc1ccc2c(-c3cccc4ccccc34)cccc2c1-c1cccc2c(-c3cccc4ccccc34)cccc12

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.47
HTR1B P28222 6/20 0.46
HTR1D P28221 2/20 0.46
CNR2 P34972 4/20 0.44
CNR1 P21554 3/20 0.44
SLC6A9 P48067 1/20 0.44
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA7 P36544 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 1/20 0.40
TNF P01375 1/20 0.40
KCNA3 P22001 1/20 0.40
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39
MCL1 Q07820 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27113961 0.95 IDO1 (0.49) IDO1HTR1BHTR1DCNR2CNR1
SCHEMBL28913624 0.93 IDO1 (0.46) IDO1HTR1BHTR1DCNR2CNR1
SCHEMBL21359802 0.92 IDO1 (0.49) IDO1HTR1BHTR1DCNR2CNR1
SCHEMBL28707126 0.88 IDO1 (0.50) IDO1HTR1BHTR1DKDM4EMEN1
SCHEMBL30660575 0.86 IDO1 (0.60) IDO1HTR1BHTR1DCNR2CNR1
SCHEMBL23581810 0.85 CNR2 (0.53) IDO1HTR1BHTR1DCNR2CNR1
SCHEMBL28703716 0.85 SLC6A9 (0.42) IDO1HTR1BHTR1DCNR2CNR1
SCHEMBL29127416 0.85 IDO1 (0.46) IDO1HTR1BHTR1DCNR2CNR1
SCHEMBL28437718 0.84 KDM4E (0.49) IDO1HTR1BHTR1DCNR2CNR1
SCHEMBL7645459 0.84 HTR1B (0.54) IDO1HTR1BHTR1DCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113474321-B Compound having binaphthyl skeleton and method for producing compound having binaphthyl skeleton 帝人株式会社 2023-12-15 CN disclosed
CN-113474321-A Compound having binaphthyl skeleton and method for producing compound having binaphthyl skeleton 帝人株式会社 2021-10-01 CN disclosed