Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 3/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | CSF1R | P07333 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 8/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 2/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544592 | 0.90 | CDK4 (0.49) | MYLK4STK17ACDK4CDK6CDK2 | |
| SCHEMBL29754277 | 0.90 | CDK4 (0.49) | MYLK4STK17ACDK4CDK6CDK2 | |
| SCHEMBL22544564 | 0.90 | CDK4 (0.54) | MYLK4STK17ACDK4CDK6CDK2 | |
| SCHEMBL29754222 | 0.90 | CDK4 (0.54) | MYLK4STK17ACDK4CDK6CDK2 | |
| SCHEMBL22544822 | 0.88 | IGF1R (0.53) | CDK2IGF1RCDK1CDK8CDK7 | |
| SCHEMBL22546075 | 0.88 | IGF1R (0.46) | MYLK4STK17ACDK4CDK6CDK2 | |
| SCHEMBL29754173 | 0.88 | IGF1R (0.46) | MYLK4STK17ACDK4CDK6CDK2 | |
| SCHEMBL22544566 | 0.86 | JAK3 (0.51) | MYLK4STK17ACDK4CDK6CDK2 | |
| SCHEMBL22544658 | 0.85 | IGF1R (0.44) | MYLK4STK17ACDK4CDK6CDK2 | |
| SCHEMBL27275338 | 0.83 | IGF1R (0.46) | MYLK4STK17ACDK2IGF1RCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993861-B | Phenyl ethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113993861-A | Phenylethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2022-01-28 | — | — | CN | disclosed |