Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 5/20 | 0.45 |
| ▸ | JAK3 | P52333 | 4/20 | 0.45 |
| ▸ | TYK2 | P29597 | 3/20 | 0.45 |
| ▸ | AXL | P30530 | 4/20 | 0.44 |
| ▸ | JAK1 | P23458 | 3/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544592 | 1.00 | CDK4 (0.49) | CDK4CDK6PIK3CDCSF1RMAP4K1 | |
| SCHEMBL22544566 | 0.94 | JAK3 (0.51) | CDK4CDK6PIK3CDCSF1RLRRK2 | |
| SCHEMBL29754222 | 0.94 | CDK4 (0.54) | CDK4CDK6PIK3CDCSF1RMYLK4 | |
| SCHEMBL22544564 | 0.94 | CDK4 (0.54) | CDK4CDK6PIK3CDCSF1RMYLK4 | |
| SCHEMBL22544822 | 0.90 | IGF1R (0.53) | CDK2 | |
| SCHEMBL28712152 | 0.90 | MYLK4 (0.45) | CDK4CDK6PIK3CDCSF1RMAP4K1 | |
| SCHEMBL29754173 | 0.90 | IGF1R (0.46) | CDK4CDK6PIK3CDCSF1RMYLK4 | |
| SCHEMBL22546075 | 0.90 | IGF1R (0.46) | CDK4CDK6PIK3CDCSF1RMYLK4 | |
| SCHEMBL22097718 | 0.87 | JAK3 (0.48) | CDK4CDK6PIK3CDCSF1RMAP4K1 | |
| SCHEMBL22544658 | 0.87 | IGF1R (0.44) | CDK4CDK6PIK3CDCSF1RMYLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259182-A1 | BENZETHERS AND ANILINES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259182-A1 | BENZETHERS AND ANILINES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | JAK3, JAK1, JAK2 | CDK4 79/4885CDK6 251/4885PIK3CD 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.