Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.61 |
| ▸ | HPGD | P15428 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | STAT1 | P42224 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297422 | 1.00 | KDM4E (0.61) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28713327 | 1.00 | KDM4E (0.61) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29479631 | 0.89 | ALDH1A1 (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL23012282 | 0.89 | ALDH1A1 (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28706406 | 0.89 | ALDH1A1 (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29479722 | 0.88 | NPC1 (0.54) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28707250 | 0.88 | NPC1 (0.54) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL23012967 | 0.85 | MAPT (0.51) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL23012765 | 0.85 | MAPT (0.51) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29479590 | 0.85 | MAPT (0.51) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |